Cannabidiol or CBD is a very effective cannabinoid which is extracted from the cannabis-based Hemp Plant. This cannabinoid is being researched for its therapeutic and medicinal benefits in alleviating a variety of health issues. The best thing about this organic remedy is it will not affect your focus or memory or will not pose any side effects on you. It is being researched that CBD largely improves your brain health. It has the ability to interact with the Endocannabinoid system found in our brain and nervous system. CBD is known for its non-psychoactive properties and will never make you high. Let us know more about the Effects of CBD on Brain further in the article.
How is CBD Different?
CBD is different from THC and other cannabinoids in many notable ways. THC the most prominent cannabinoid found in the same cannabis plant is the psychoactive one. It is responsible for inducing a high. This cannabinoid prominently interacts with CB1 and CB2 receptors while CBD does not bind with these receptors and has a very little effect on them. It counters the effects of THC and acts as an antagonist thus stopping it from inducing a high.
Also, THC has some side effects such as paranoia, nervousness, shortness of breath, memory loss, Lung Problems and more. While CBD does not pose any side effects. You do not get high or have to go through any such problematic side effects.
Effects of CBD on Brain
CBD is a very effective cannabinoid known for its amazing medicinal properties. It is also being researched for treating cancer, the life-taking disease. Let us find out how CBD affects our body as well as brain:
Neurological Effects of CBD:
CBD has many beneficial effects and among these, its effect on epilepsy patients is really important. CBD has reportedly shown a reduction in the frequency of seizures in epilepsy. Studies suggest that CBD possesses various neurological effects that can help in maintaining our brain’s health.
Another latest study that was done by the King’s College London research team stated that CBD can be a favorable option in lowering the psychosis activity in the brain. It can also be used to treat different mental conditions such as ADHD, anxiety, schizophrenia, and others.
Neuroprotective Effects of Cannabidiol is said to possess neuroprotective properties as it protects the neurons from degradation. CBD can be used for the treatment of many neurological diseases.
Alzheimer’s Disease is a very common condition that occurs due to the degeneration of neurons. CBD has shown a positive impact in treating such disease. CBD for Alzheimer’s can be used to alleviate the symptoms of the AD as well.
Anti-Tumor effects of CBD
Studies have suggested that CBD can also be used to reduce cancer-related symptoms as well as reduce the growth of cancerous tumors.
According to a study done in 2016, CBD and other cannabis compounds can reduce the growth of tumor in animal models. Thus, CBD can be considered as an option to treat symptoms related to cancer. Though a lot of research needs to be done in this area.
Painkilling Effects of CBD
When the brain sends signals to the pain receptors in our body, we feel the sensation of pain. Researches have been conducted that show the potential benefits of CBD in reducing pain.
People are using CBD oil and getting relief in various types of pain. CBD has become an effective remedy for treating chronic pain as well as pain from multiple sclerosis, cancer pain, arthritis pain, and pain arising from Fibromyalgia as well.
Anti-anxiety effects of CBD
In a study done in 2011, 24 patients suffering from social anxiety disorder were administered with CBD and placebo.
The results stated that the patients who were treated with CBD experienced a relief in anxiety and discomfort that those treated with placebo.
Working of CBD in Brain
As we all know, our body has an Endocannabinoid System that helps in the regulation of different body functions such as pain, mood, appetite and immunity system. CBD is said to bind with the receptors present in the ECS. It does not really bind well with the CB1 and CB2 receptors found in the ECS, but it does bind well with many other receptors.
Let us know more about these receptors:
CBD has a higher affinity with the serotonin receptors and provides a lot of therapeutic properties. It targets the 1A serotonin receptor specifically.
These receptors regulate the release of cortisol hormones. This hormone is responsible for metabolism and reactions to stress. It is also said that low serotonin receptors can cause depression.
CBD when consumed triggers the serotonin receptors and reduces stress and problems such as depression, stress, sleep issues, nausea, and more.
CBD binds well to the TRPV1 receptors also known as the vanilloid receptors. One of the most important functions of these receptors is to manage the temperature of the body. it is responsible for maintaining the thermoregulation in the body.
CBD binds with these receptors and helps in maintaining the temperature in our body. It can help in maintaining normal body balance thus reducing inflammation and pain.
These receptors are also known as GPR55 receptors are being researched for its family of receptors. These receptors are responsible for maintaining blood pressure, bone density, and bone reabsorption.
But, if overly activated these receptors can be harmful to our body and can lead to osteoporosis. This receptor also helps in the migration and multiplication of cancer cells. CBD can inhibit the growth of orphaned receptors and can also be used as an effective remedy for inhibiting the growth of cancer cells.
Peroxisome proliferator-activated receptors (PPARs)
Also known as Nuclear receptors, PPARs are found on the surface of the nucleus of a cell. These receptors bind with CBD and produce PPAR-gamma which can be helpful in the multiplication of cancer cells.
Thus, PPARs and CBD can together be very effective in reducing cancer cells.
Anandamide is one of the major endocannabinoid found in the ECS and has neuroprotective properties. This endocannabinoid is made only when it is needed by the body.
CBD modifies the concentration of Anandamide. It makes an enzyme called FAAH, which is responsible for the metabolism of anandamide inhibiting its breakdown. Thus, CBD inhibits FAAH to break down anandamides and increases its impact on the system.
Potential of CBD
A lot of studies suggest that CBD has great therapeutic benefits in alleviating a number of health issues such as anxiety, depression, stress, ADHD, chronic pain and many more. Though a lot needs to be researched in this field CBD can improve human health and can help lead a happy life.
We hope you enjoyed this article on the effects of CBD on Brain. If you have any suggestions for us, please drop them in the comment section below.