The two most prominent cannabinoids (compounds found inside the cannabis plant) are THC and CBD.THC comprises the main psychoactive component of cannabis and is the chemical compound that causes users to become intoxicated. CBD, however, has no psychoactive properties and is responsible for most of the medical advantages associated with cannabis.
However, in recent years, a third promising chemical compound, CBN (cannabinol), has emerged that is found in the subspecies of Cannabis Sativa, Indica, and Afghanica that offers many therapeutic effects. It functions as a weak agonist, meaning a substance that attaches onto a receptor, and elicits a biological response. It activates the related neurological receptors increasing the positive cannabis attributes. CBN is produced as THC degrades once the cannabis is harvested, with the tetrahydrocannabinol losing its characteristic intoxicating properties. As the psychoactive THC compound gets exposed to UV rays and oxygen in the air, it begins to shed hydrogen molecules, changing into CNBA initially, and later into CBN.
In this article, we will examine the difference between two different types of cannabinoids namely CBD and CBN. Apart from CBD and CBN, the other different types of cannabinoids are CBG, CBC, CBDA, and many more.
Medical Applications of CBD and CBN
CBD constitutes a major cannabinoid that has key medicinal applications. Its psychoactive properties are comparatively less in comparison to THC. It is used to treat medical ailments such as migraines, schizophrenia, epilepsy beyond spasms. Moreover, it has received attention for its relaxing and anxiety-reducing properties. In addition, CBD has been found to function as a highly effective anticonvulsant and offers hope in treating disorders like MS, epilepsy, and muscle spasms among others. It also holds promise in decreasing the neurotoxins in the brain subsequent to brain damage after head trauma or stroke. This has led researchers to believe that CBD may offer some form of protection against MDMA-based neurotoxins or permanent reduction of the serotonergic receptions.
Benefits of CBD
CBD help in alleviating the symptoms of numerous health issues such as anxiety depression, cold and cough, and many more discussed below. Check out the health benefits of CBD:
- Pain Relief
CBD may be beneficial at reducing chronic pain by interacting with the body’s endocannabinoid system, according to research. Seven patients who had recently received a kidney transplant were given 50 to 150 mg of CBD twice daily for three weeks in a 2018 study. Two patients experienced complete pain relief, four experienced moderate pain relief, and one patient experienced no change.
According to research, CBD helps in alleviating the symptoms of cancer such as nausea, and pain.
CBD may potentially have anticancer properties, according to some preliminary research. A review of papers published in 2019 revealed that CBD may help reduce tumor development and promote tumor cell death, according to a review of in vitro and in vivo research. Pancreatic cancer was the focus of the research.
CBN or Cannabinol is produced as a metabolite of THC. It carries a reduced potential of generating euphoria since it is not a psychoactive cannabinoid. Nevertheless, it may render the user sluggish and dizzy.CBN is reputed to be an anxiolytic; it reduces muscle spasms as it is an antispasmodic component and assists in relieving the symptoms of glaucoma. Research is being conducted on CBN and its medicinal applications. Researchers have also found CBN to accelerate bone healing. It has been shown to cause a significant improvement in the treatment of burns. One of its primary uses is in treating insomnia. Finally, it also has proved useful in treating chronic ailments like Parkinson’s and multiple sclerosis.
Its other benefits include:
- Increases Appetite
- Bone Formation and Healing
- Chronic Pain Alleviation
- Anti-Cancer effect
Sleep and Alertness
Cannabinol, or CBN, is a moderately psychoactive cannabinoid with sedative properties. It’s possible that it’s the most powerful sedative of all the cannabinoids. Because of the sedation, it is an effective sleep aid and therapy for insomnia. CBN aids at the beginning of sleep and the duration of sleep. It also helps you stay awake during the day by reducing sleepiness. Year after year, one out of every four persons suffers from insomnia that lasts days or weeks. It aids in the lulling of patients to sleep and the recovery of long-term sleep. Cannabinol might be the secret to feeling energized first thing in the morning. When you use CBN, this ‘refresh’ keeps you energetic all day. More study into the specific mechanisms that help with sleep and wakefulness is required.
Does CBD Or CBN Get You High?
CBD is entirely not psychoactive, so it doesn’t make you high. The Majority of CBD products have extremely low THC and high CBD content. It is the second most abundant compound in the plant.
CBD is sold in a variety of forms mentioned below:
- Oil and Tinctures
- Creams and Lotions
- Capsules and Pills
CBN is regarded as mildly psychoactive. It doesn’t cause a high similar to THC. THC is the compound responsible for the psychoactive effects of cannabis, while CBD and CBN are not psychoactive themselves. Moreover, CBD can mitigate the negative effects of a THC high, and calms the user from anxiety and delusions.
Legality Of CBN And CBD- CBD vs CBN
The demand for the hemp-sourced compound Cannabidiol (CBD) has peaked. It has been legalized in all 50 states. But the key determinant regarding its legality is based on whether the CBD has been sourced from hemp or if it is extracted directly from marijuana plants.
Since hemp consists of less than 0.3% psychoactive THC or Tetrahydrocannabinol it does not make you high, it is considered legal across various industries and American retailers. But marijuana extracted CBD that includes 30% THC is regarded as completely illegal in some states, while in some other states it is completely legal albeit with plenty of regulations. In a majority of states, marijuana-produced CBD is something of a mixed bag, as every state has its laws regarding CBD products.
The scenario in 2018 reveals the legalization of CBD products relating to medical purposes, whether derived from hemp or marijuana in 29 American states. However, in 4 American states, marijuana-sourced CBD is held illegal, though the laws are still being reviewed.
Cannabinol (CBN) is mildly psychoactive but is not included in the United Nations’ Narcotic Drugs Convention on Psychotropic Substances. So the signatory nations of these global drug treaties are not bound to regulate CBN.
In Canada, CBN is a controlled substance under Schedule II of their Act while in the UK, it’s a drug of the category Class B under their Misuse of Drugs Act. However, in the USA, CBN is not included in the Scheduled Controlled list of substances.
Mechanisms of Production
Cannabis produces cannabigerol acid that blends with different substances to generate THCA and CBDA. Both THCA and CBDA are the acid versions of both THC plus CBD. This occurs within the live plant. After cultivating, the cannabinoids require the process of decarboxylation which is performed by heating the plant for efficacy. Heating discharges CBD out of CBDA.
CBN is generated from both decarboxylations as well as aging. The process of decarboxylation disintegrates THC into CBN. The aging method, being a slow process, is time-consuming. CBD is not generated through the aging method.
The Action Mechanism of CBD And CBN
Both CBD and CBN trigger the cannabinoid receptor lodged with the Endocannabinoid system (ECS). The two cannabinoid receptors are CB1 and CB2, with CB2 receptors existent only within the peripheral tissues, while CB1 receptors are situated inside the brain plus the peripheral tissues. These receptors promote cellular mechanisms via signal transduction that monitors different systems and lowers anxiety, pain, as well as muscular spasms.
Are There Side Effects Of CBD And CBN?
CBN or Cannabinol along with the endocannabinoid system spans through the entire human body and regulates a wide array of bodily functions including mood, appetite regulation, metabolism, immune response, sleep patterns, and many more. The benefits of CBD and CBN greatly outweigh the mild side effects that may come with consuming them. While Using a CBD product, one can get a dry mouth, but if it is being taken to treat the effects of cancer, such side effects hardly matter.
CBD products do not lead to hair loss or stomach issues. Compared to its medical utility, the side effects of CBD pale in comparison. That being said, if you are taking blood pressure drugs, the consumption of CBD may make them less effective.
CBN like CBD does not carry any prominent side effects, though it functions as a sedative if that is considered to be negative a side effect. Broad Spectrum CBN Tincture is perfect for individuals who want to hone in on the medical benefits of both CBD and CBN.
Final Summing Up
In finality, our focus on THC, as well as CBD, has always remained high, but the huge medicinal capacity of CBN cannot be underrated. It is a highly effective sedative with only 10% of the psychoactive impact of THC.
CBN will not make you intoxicated or high. If you are affected by insomnia, Cannabinol could be a good option for you.
Besides it also has useful application as an anticonvulsant and the warding off of inflammation and bacteria.