Cannabidiol (CBD) has long remained in the limelight as a likely cure, or at least palliative therapy, for different types of cancer. Research is continuing on how and whether this truly works as the antitumor features of CBD oil can be beneficial in managing the different stages of mesothelioma. Moreover, there are strong indications that cannabis could aid patients suffering from mesothelioma.
This article delves into how CBD can be helpful for individuals affected with mesothelioma and manage its symptoms. Let’s also take a look at what research says about the benefits conferred by CBD on this cancer type.
Table of Contents
An Overview Of Mesothelioma
Malignant mesothelioma comprises a type of cancer happening in the thin layer of tissue enveloping most of the internal organs. It’s an extremely aggressive kind of cancer that is generally fatal. But though a cure isn’t possible still, treatments are present for mesothelioma.
You carry a coating of specific cells termed mesothelial cells covering the inside of your chest, abdomen, and the area enclosing your heart. Mesothelial cells also envelop many of your internal organs’ external surfaces. This cover that the cells develop is called the mesothelium.
Your mesothelium creates a kind of lubricating fluid that safeguards your organs by permitting them to drift against one another. For example, the fluid aids your lungs to expand and contract within your chest as you breathe. Your mesothelium is termed differently in different parts of your body, like:
- Peritoneum: Covers most of your abdomen’s organs and the interior of your abdomen itself.
- Tunica vaginalis: Pouch membrane enveloping the testicles.
- Pleura: Lines the chest space containing your lungs along with your lungs themselves.
- Pericardium: Lines your heart, forming the space supporting your heart in your chest.
Mesothelial tumors may develop in any one of these coverings, and they might be non-cancerous (benign) or cancerous (malignant). Mesothelioma comprises the cancerous tumor.
Surgeons can generally get rid of benign tumors surgically, and patients frequently don’t need any extra treatment after the tumor has been eliminated.
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Causes Of Mesothelioma
Working with asbestos is the main risk factor for mesothelioma. Asbestos comprises a mineral group having thin, microscopic fibers. As the fibers are resistant to heat, chemicals, and fire and don’t conduct electricity, workers have been utilizing and mining asbestos in the construction, automotive, and other industries extensively.
Individuals can swallow or inhale small asbestos fibers when they get airborne, as during the manufacturing process. When this occurs, it can lead to grave health issues. Asbestos exposure in the workplace connects to 75% of mesothelioma cases.
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Symptoms Of Mesothelioma
Mesothelioma symptoms differ and are based on where your cancer happens.
Pleural mesothelioma results in symptoms like:
- Painful coughing
- Unexplained loss of weight
- Chest pain below the rib cage
- Shortness of breath
- Strange tissue lumps beneath your chest skin
Peritoneal mesothelioma leads to symptoms like:
- Abdominal pain and swelling
- Lumps of abdomen tissue
- Unexplained loss of weight
Pericardial mesothelioma leads to symptoms like breathing difficulty and chest pains, while tunica vaginalis mesothelioma results in swelling or a mass on a testicle.
How CBD Can Manage Mesothelioma
Most studies concerning cancer and cannabis are targeted at more popular types of cancer. Researchers need to carry out more intensive investigations into the said health support of CBD in managing this condition. Nonetheless, the efficiency of cannabis in treating and stopping cancer growth is unquestionable. Cannabis acts in various ways to kill cancer cells and so CBD for Mesothelioma has great potential.
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CBD Halts The Proliferation Of Cancer Cells On The Spot
Cancer cells won’t die by themselves; naturally, they will split and spread across the body ultimately resulting in a tumor. Cannabis contains CBD and THC, both of which have been revealed to exert antiproliferative effects on cancer cells. Utilizing cannabinoid therapy has been said to effectively half the development of tumors in animal and cellular models.
CBD Results In Cancer Cell Death
Research displays that CBD and THC promote programmed cell death (apoptosis) in many types of cancer.
CBD Has Anti-metastatic Properties
Cancer cells can disintegrate tumors and move in the bloodstream, spreading to various parts of the body. Once cancers get metastatic, they become considerably more hard to treat and the prognosis gets poor. Studies display that in both cellular and animal models, THC and CBD have valuable anti-metastatic properties. The laboratory proof informs us that cannabis has properties that can aid stop cancers from spreading, which is especially vital in aggressive cancers like mesothelioma.
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CBD Starves Cancer Cells
Tumors can only advance by growing their own blood vessels where it gets oxygen and different nutrients from various parts of the body. This process is termed angiogenesis. Studies reveal that both CBD and THC can prevent tumors from developing their individual blood vessels. This stops the tumor from drawing nutrition from the body that would permit it to develop and spread.
There’s strong evidence upholding the theory that cannabinoids can decrease tumor growth in animal models of cancer. CBD may also boost uptake or raise the potency of specific drugs utilized to treat cancer.
Here are a few encouraging studies:
- A 2019 review of in vivo and in vitro studies highlighting pancreatic cancer discovered that cannabinoids can aid retard tumor growth, lessen tumor invasion, and cause tumor cell death. The study authors stated that research into the effectiveness of various formulations, dosing, and exact mode of action is deficient and urgently required.
- A 2019 study suggested that CBD could induce cell death and render glioblastoma cells more sensitive to radiation, but without effect on healthy cells.
- A 2014 study in experimental models of colon cancer in vivo indicates that CBD may restrict the development of colorectal cancer cells.
- A 2014 review of 35 in vitro and in vivo studies discovered that cannabinoids are encouraging compounds in the treatment of gliomas.
- Research from 2010 showed the efficiency of CBD in preclinical models of metastatic breast cancer. The study discovered that CBD substantially lowered breast cancer cell multiplication and invasion.
These are simply some studies addressing the capacity of cannabinoids to aid treat cancer. CBD shouldn’t be regarded as a replacement for different cancer treatments.
A few areas for upcoming research include:
- The effects of CBD with and without different cannabinoids such as THC
- The effects of various administration techniques
- Effective and safe dosing
- How CBD acts on specific kinds of cancer
- How CBD interacts with chemotherapy drugs and different cancer treatments
As A Complementary Treatment For Cancer
Cancer treatments like chemotherapy and radiation can generate an assortment of side effects, such as loss of appetite and nausea, which can cause weight loss.
Research indicates that cannabinoids may relieve neuropathic pain and nausea. THC has revealed better poor appetite due to cancer and cancer therapy, while CBD can lower it. CBD is also believed to have anti-anxiety, antioxidant, anticonvulsant, and anti-inflammatory properties.
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CBD Oil For Treating Cancer
Cannabidiol (CBD) oil comprises a product sourced from cannabis, though it is non-psychoactive. CBD is among numerous cannabinoid compounds that are present in cannabis naturally. But in contrast to delta-9-tetrahydrocannabinol or THC, utilizing CBD oil does not get you high. That is why CBD oil is a likely contender for various medical applications. CBD can be consumed by mouth and is employed for various diseases, though there is no proof that it is effective to heal anything.
No clinical studies have been done on CBD oil simply for pleural mesothelioma patients. But there is some proof there could be anti-tumor properties hidden in the oil. In different animal studies, CBD has restricted the growth of lung cancer, glioblastoma, breast cancer, colon cancer, and prostate cancer.
A clinical study in the UK indicated life expectancies could be more. CBD extracts were administered to mice that possessed pancreatic cancer. This kind of study is happy news for patients with difficult-to-treat cancers such as mesothelioma. While the evidence emerges from lab animal studies, optimism prevails results could be beneficial for humans, also. If that is the instance, CBD for Mesothelioma could be useful in enhancing life expectancy for mesothelioma and different aggressive cancers.
CBD oil possesses a reputation for providing alleviation from cancer symptoms, along with cancer treatment symptoms. Various severe symptoms can be handled with CBD. In one clinical study, clinical researchers matched the results of CBD and THC on patients. The researchers discovered that patients that got CBD had greater pain relief. Other symptoms that CBD can aid with include vomiting and nausea resulting from stress, insomnia, chemotherapy, and anxiety.
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The Best CBD Products For Mesothelioma
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ThoughtCloud’s different product categories include Full-Spectrum CBD, Isolate CBD, and Cloud Supplies, among other products.
CBD for Mesothelioma shouldn’t be applied as an alternative cancer treatment. More rigorous studies are needed into the potential advantages and dangers of CBD dosing, administration, and how it impacts other cancer treatments. Presently, there are no FDA-endorsed CBD products for cancer. So, besides Epidiolex for epilepsy, the products that are present haven’t been assessed by the FDA.
However, some people are employing cannabinoids to relieve the side effects of cancer treatment. Since CBD can interact with different cancer therapies, it’s prudent to verify with your physician before you begin taking it.